Preheat the oven to 400º Fahrenheit. Spray a 9" round deep dish pie plate (or cake pan) with cooking spray.
Using a skillet over medium heat, brown the ground beef until the beef is no longer pink. Drain off any fat.
Add in the taco seasoning and drained Rotel. Mix well and heat through.
Spread the beef mixture in the bottom of the prepared pie plate. Sprinkle the shredded cheese over the top.
In a small bowl, whisk together the Bisquick mix, milk and eggs.
Pour evenly over the beef and cheese.
Bake for 25-30 minutes or until the middle of the pie is set and the top is golden brown. A knife inserted in the center should come out clean.
The calories shown are based on the pie being cut into 8 pieces, with 1 serving being 1 slice of impossible pie. Since different brands of ingredients have different nutritional information, the calories shown are just an estimate. **We are not dietitians and recommend you seek a nutritionist for exact nutritional information.**